MES–ERP Lot Sync: 5 Critical Pitfalls
A practical checklist to prevent lot-breakage costs in chem and pharma.
5 sources of lot breakage
Shift change, manual barcode, ERP lag, wrong UoM, and hold flag sync — unsolvable without a MES event bus.
API-first sync
Idempotent lot API, outbox pattern, and ERP ack timeout — the minimum set for lot integrity in chem and pharma.
Lot split/merge events on the MES event bus; ERP receives consolidated state only, intermediate steps stay in the historian.